This manual was compiled by the Global Taskforce on Cholera Control (GTFCC) and developed from the input and contributions of experts from partner institutions, including Action Contre la Faim (ACF), Agence de Médecine Préventive (AMP), United States Centers for Disease Control and Prevention (CDC), Epicentre, European Centre for Disease Prevention and Control (ECDC), Federal Ministry of Health and Human Service, Federal Government of Somalia, International Centre for Diarrhoeal Disease Research—Bangladesh (icddr,b), Institut Pasteur, International Federation of Red Cross and Red Crescent Societies (IFRC), International Vaccine Institute (IVI), Johns Hopkins Bloomberg School of Public Health (JHSPH), Medair, Federal Ministry of Health—Nigeria, Médecins Sans Frontières (MSF), National Institute of Cholera and Enteric Diseases—India (NICED), Pan American Health Organization (PAHO), Partners In Health (PIH), Save the Children, Tufts University, United Nations Children’s Fund (UNICEF), Université Aix-Marseille, University of Florida and the World Health Organization (WHO). This work was supported by a grant from the Bill & Melinda Gates Foundation.